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L-lysine biosynthesis III

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
L-aspartate + ATP <=> L-4-aspartyl_phosphate + ADP 2.7.2.4 aspartate kinase

(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NADP+ + H2O <=> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+ 1.17.1.8 4-hydroxy-tetrahydrodipicolinate reductase

meso-2,6-diaminoheptanedioate + H+ <=> L-lysine + CO2 4.1.1.20 diaminopimelate decarboxylase

H+ + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O <=> L-2-amino-6-oxopimelate 0.0.0.0
3.5.99


L-aspartate_4-semialdehyde + phosphate + NADP+ <=> L-4-aspartyl_phosphate + NADPH + H+ 1.2.1.11 aspartate-semialdehyde dehydrogenase

pyruvate + L-aspartate_4-semialdehyde <=> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O + H+ 4.3.3.7 4-hydroxy-tetrahydrodipicolinate synthase

meso-2,6-diaminoheptanedioate + NADP+ + H2O <=> L-2-amino-6-oxopimelate + NH3 + NADPH + H+ 1.4.1.16 diaminopimelate dehydrogenase

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